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References
Barnes, M. A., Carson, M. J., & Nair, M. G. (2015). Non-traditional cytokines: How catecholamines and adipokines influence macrophages in immunity, metabolism and the central nervous system. Cytokine, 72(2), 210–219. https://doi.org/10.1016/j.
Bluthe, R. M., Pawlowski, M., Suarez, S., Parnet, P., Pittman, Q., Kelley, K. W., & Dantzer, R. (1994). Synergy Between Tumor Necrosis Factor alpha and Interleukin-1 in the Induction of Sickness Behavior in Mice. Psychoneuroendocrinology, 19(2), 197–207.
Bluthé, R. M., Beaudu, C., Kelley, K. W., & Dantzer, R. (1995). Differential effects of IL-1ra on sickness behavior and weight loss induced by IL-1 in rats. Brain Research, 677(1), 171–176. https://doi.org/10.1016/0006-
Bluthe´, R.-M., Dantzer, R., & Kelley, K. W. (1992). Effects of interleukin-1 receptor antagonist on the behavioral effects of lipopolysaccharide in rat. Brain Research, 573(2), 318–320. https://doi.org/10.1016/0006-
Capuron, L., Hauser, P., Hinze-Selch, D., Miller, A. H., & Neveu, P. J. (2002). Treatment of cytokine-induced depression. Brain Behavior and Immunity, 16(5), 575–580. https://doi.org/10.1016/s0889-
Carpenter, L. L., Shattuck, T. T., Tyrka, A. R., Geracioti, T. D., & Price, L. H. (2011). Effect of childhood physical abuse on cortisol stress response. Psychopharmacology, 214(1), 367–375. https://doi.org/10.1007/
Cohen, S., Janicki-Deverts, D., Doyle, W. J., Miller, G. E., Frank, E., Rabin, B. S., & Turner, R. B. (2012). Chronic stress, glucocorticoid receptor resistance, inflammation, and disease risk. Proceedings of the National Academy of Sciences, 109(16), 5995–5999. https://doi.org/10.1073/pnas.
Dantzer, R., Bluthé, R. M., Gheusi, G., Cremona, S., Layé, S., Parnet, P., & Kelley, K. W. (1998). Molecular basis of sickness behavior. Annals of the New York Academy of Sciences, 856, 132–138. Retrieved from http://www.ncbi.nlm.nih.gov/
Dantzer, R., Bluthe, R. M., & Kelley, K. W. (1991). Androgen-dependent vasopressinergic neurotransmission attenuates interleukin-1-induced sickness behavior. Brain Research, 557(1–2), 115–120. https://doi.org/10.1016/0006-
Dantzer, R., Wollman, E. E., & Yirmiya, R. (Eds.). (1999). Cytokines, Stess, and Depression. New York, NY: Kluwer Academic / Plenum Publishers.
Davis, K. C., & Raizen, D. M. (2017). A mechanism for sickness sleep: lessons from invertebrates. Journal of Physiology, 595(16), 5415–5424. https://doi.org/10.1113/
Dong, J., Li, J., Cui, L., Wang, Y., Lin, J., Qu, Y., & Wang, H. (2018). Cortisol modulates inflammatory responses in LPS-stimulated RAW264.7 cells via the NF-ΚB and MAPK pathways. BMC Veterinary Research, 14(1), 1–10. https://doi.org/10.1186/
Dunn, A. J. (2000). Cytokine Activation of the HPA Axis. Annals of the New York Academy of Sciences, 917(1), 608–617. https://doi.org/10.1111/j.
Fischer, S., Strawbridge, R., Vives, A. H., & Cleare, A. J. (2017). Cortisol as a predictor of psychological therapy response in depressive disorders: Systematic review and meta-analysis. British Journal of Psychiatry, 210(2), 105–109. https://doi.org/10.1192/bjp.
Flierl, M. A., Rittirsch, D., Huber-Lang, M., Sarma, J. V., & Ward, P. A. (2008). Catecholamines-crafty weapons in the inflammatory arsenal of immune/inflammatory cells or opening pandora’s box? Molecular Medicine (Cambridge, Mass.), 14(3–4), 195–204. https://doi.org/10.2119/2007-
Foley, P., & Kirschbaum, C. (2010). Human hypothalamus-pituitary-adrenal axis responses to acute psychosocial stress in laboratory settings. Neuroscience and Biobehavioral Reviews, 35(1), 91–96. https://doi.org/10.1016/j.
Irwin, M. R., & Miller, A. H. (2007). Depressive disorders and immunity: 20 years of progress and discovery. Brain, Behavior, and Immunity, 21(4), 374–383.
Juster, R. P., McEwen, B. S., & Lupien, S. J. (2010). Allostatic load biomarkers of chronic stress and impact on health and cognition. Neuroscience and Biobehavioral Reviews, 35(1), 2–16. https://doi.org/10.1016/j.
Maier, S. F., & Watkins, L. R. (1998). Cytokines for psychologists – Implications of bidirectional immune-to-brain communication for understanding behaviour, mood and cognition. Physiol. Rev., 105(1), 83–107.
Miller, A. H., Pariante, C. M., & Pearce, B. D. (1999). Effects of Cytokines on Glucocorticoid Receptor Expression And Function. Cytokines, Stress, and Depression, 461, 107–116. https://doi.org/10.1007/978-0-
Miller, A. H., & Raison, C. L. (2016). The role of inflammation in depression: from evolutionary imperative to modern treatment target. Nature Reviews Immunology, 16(1), 22–34. https://doi.org/10.1038/nri.
Miller, G. E., Chen, E., & Zhou, E. S. (2007). If it goes up, must it come down? Chronic stress and the hypothalamic-pituitary-
Miller, G. E., Cohen, S., & Ritchey, A. K. (2002). Chronic psychological stress and the regulation of pro-inflammatory cytokines: A glucocorticoid-resistance model. Health Psychology, 21(6), 531–541.
Osburg, B., Peiser, C., Dömling, D., Schomburg, L., Ko, Y. T., Voigt, K., & Bickel, U. (2002). Effect of endotoxin on expression of TNF receptors and transport of TNF-alpha at the blood-brain barrier of the rat. American Journal of Physiology – Endocrinology and Metabolism, 283(5), E899–E908. https://doi.org/10.1152/
Pace, T. W. W., & Miller, A. H. (2009). Cytokines and glucocorticoid receptor signaling: Relevance to major depression. Annals of the New York Academy of Sciences, 1179, 86–105. https://doi.org/10.1111/j.
Pan, W., Stone, K. P., Hsuchou, H., Manda, V. K., Zhang, Y., & Kastin, A. J. (2011). Cytokine signaling modulates blood-brain barrier function. Current Pharmaceutical Design, 17(33), 3729–3740. https://doi.org/10.1016/j.
Phelps, C., & Korneva, E. (Eds.). (2008). Cytokine Receptors in the Brain. Amsterdam, The Netherlands: Elsevier B.V. https://doi.org/10.1016/S1567-
Powers, S. I., Laurent, H. K., Gunlicks-Stoessel, M., Balaban, S., & Bent, E. (2016). Depression and anxiety predict sex-specific cortisol responses to interpersonal stress. Psychoneuroendocrinology, 69, 172–179. https://doi.org/10.1016/j.
Ramer-Quinn, D. S., Baker, R. A., & Sanders, V. M. (1997). Activated T helper 1 and T helper 2 cells differentially express the beta-2-adrenergic receptor: a mechanism for selective modulation of T helper 1 cell cytokine production. Journal of Immunology (Baltimore, Md. : 1950), 159(10), 4857–4867. Retrieved from http://www.jimmunol.org/
Schoenborn, J. R., & Wilson, C. B. (2007). Regulation of Interferon-γ During Innate and Adaptive Immune Responses. Advances in Immunology, 96(07), 41–101. https://doi.org/10.1016/S0065-
Segerstrom, S. C., & Miller, G. E. (2004). Psychological Stress and the Human Immune System: A Meta- Analytic Study of 30 Years of Inquiry. Psychological Bulletin, 130(4), 601–630. https://doi.org/10.1016/j.
Sehic, E., & Blatteis, C. M. (1996). Blockade of lipopolysaccharide-induced fever by subdiaphragmatic vagotomy in guinea pigs, 726, 160–166.
Shariq, A. S., Brietzke, E., Rosenblat, J. D., Barendra, V., Pan, Z., & McIntyre, R. S. (2018). Targeting cytokines in reduction of depressive symptoms: A comprehensive review. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 83(October 2017), 86–91. https://doi.org/10.1016/j.
Shonkoff, J. P., Garner, A. S., Siegel, B. S., Dobbins, M. I., Earls, M. F., Garner, A. S., … Wood, D. L. (2012). The Lifelong Effects of Early Childhood Adversity and Toxic Stress. Pediatrics, 129(1), e232–e246. https://doi.org/10.1542/peds.
Skelly, D. T., Hennessy, E., Dansereau, M. A., & Cunningham, C. (2013). A Systematic Analysis of the Peripheral and CNS Effects of Systemic LPS, IL-1Β, TNF-α and IL-6 Challenges in C57BL/6 Mice. PLoS ONE, 8(7), 1–20. https://doi.org/10.1371/
Sofroniew, M. V. (2015). Astrocyte barriers to neurotoxic inflammation. Nature Reviews Neuroscience, 16(5), 249–263. https://doi.org/10.1038/
Varatharaj, A., & Galea, I. (2016). The blood-brain barrier in systemic inflammation. Brain, Behavior, and Immunity, 60, 1–12. https://doi.org/10.1016/j.bbi.
Wichmann, S., Kirschbaum, C., Böhme, C., & Petrowski, K. (2017). Cortisol stress response in post-traumatic stress disorder, panic disorder, and major depressive disorder patients. Psychoneuroendocrinology, 83(January), 135–141. https://doi.org/10.1016/j.
Xaio, H., Banks, W. A., Niehoff, M. L., & Morley, J. E. (2001). Effect of LPS on the permeability of the blood-brain barrier to insulin. Brain Research, 896(1–2), 36–42. https://doi.org/10.1016/S0006-
Zadka, Ł., Dzięgiel, P., Kulus, M., & Olajossy, M. (2017). Clinical Phenotype of Depression Affects Interleukin-6 Synthesis. Journal of Interferon & Cytokine Research, 37(6), 231–245. https://doi.org/10.1089/jir.
Zhou, J., Yan, J., Liang, H., & Jiang, J. (2014). Epinephrine Enhances the Response of Macrophages under LPS Stimulation. BioMed Research International, 2014, 1–9. https://doi.org/10.1155/2014/
The Daily Solutions Podcast – Our Top 5 Episodes from December
Since a new episode is released, every day, we thought we should do a roundup of some the top episodes so far to keep you from missing out on important topics in the floatation community.
Behold the creme de la creme of podcastery, if you will. Here they are, in chronological order
Should I Have One or Multiple Styles of Float Tank?
If you had every model and type of float tank you’d be running the Burj Khalifa of float centers, with an estimated 38 unique float tanks, which include pods, custom open pools, cabins, vertical tanks, and inflatable or portable float devices currently on the market (not even counting old models).
This is all to say that there are a ton of options out there when considering tanks for your center.
Whether you’re opening a two-tank center, or a bajillion-tank center, do you want all the same model, or will you have some variety?
Why ROI Calculators Suck! (or at least why you should use caution)
“What is an ROI calculator?” I hear you asking. “ROI” simply stands for “Return on Investment”. An “ROI Calculator” is just a tool that outlines the cost of something and generates what your anticipated profit will be over a certain length of time. Usually annually.
We should make a distinction between a simple ROI calculator (i.e. a widget built into a website with limited inputs), and a financial plan (complete with P&L, cashflow, and balance sheets). Both are going to try and do the same thing, but one is going to be far more detailed and accurate.
Roughly what we’re going to be talking about is a return on investment for your whole business, but return on investment can (and should) be used for lots of different aspects to your business to help you determine how best to spend your company’s money. Usually, though, that’s going to require a lot of detail that a simple widget can’t provide.
How to compete on price without slashing prices
Let’s say you’re a float tank center and more centers are starting to show up in your town…
Or, maybe you are that other center starting up a town that already has float tanks…
As new centers enter the market, the typical response is to run promotions on daily deal sites, promote large specials, and/or run Facebook Ads selling floats for much less than the usual offerings.
The best case scenario is this price slashing behavior subsides shortly after the neighboring center opens.
But what if it doesn’t? What if an existing competitor decides their new price is even lower?
How do you compete with a price slashing neighbor without competing on price?
Learn a few ways to make price a non issue with your customers…
Float On’s Halloween Spooktacular!
‘Twas briny, and the epsom groves fluttered with salt-bats, a lurking fog floating atop the murky bog. From the dark maw of silence came a guttural groan, an eerie utterance akin to those of monsters. From the depths of darkness, that groan turned into what mortals...
Timeline for Opening Up a Float Center
Opening up a float center is a lot like climbing a mountain. Even if you can see the peak, it’s a lot further away than you think, and when you finally get there, the journey and the destination usually end up being different than previously assumed.
In this post we’ll lay out a general process and timeline of what you may encounter on your path, from initial idea to actually operating a center.
Can you have volunteers at your center?
So you’re thinking about using volunteers in your float center?
Before we clarify what a “volunteer” actually means, we’ll first explore why a float center might be considering them in the first place. While it can be a way to provide floats to people who are otherwise unable to pay, the impulse to bring in volunteers can also stem from a desire to get some sort of free labor (later in this post we’ll dive into why you can’t actually do this, but it’s important to recognize that the instinct is understandable, especially when you have someone lined up and willing to work for free).
In addition to a desired boost in overall productivity, it’s also a way to invite more people into your center to experience what you do. Some customers actually want to help out and see what happens behind the scenes at a center.
Floating and Athletics, a Strong Relationship
One of the beautiful things about the float tank is that it serves to rejuvenate the whole person. — the body, mind, heart.
Broadly speaking, it’s a tool for homeostasis, an ideal environment that supports balance, health, and growth. This piece will look specifically at floating and athletics. For anyone who defines themselves as an athlete, or as a general pursuant of athletic endeavors, the float tank can be a powerful asset.
In this post, I’ll discuss individual athletes who float and how to look at this from a marketing perspective. I’ll also discuss past and present research, and share some thoughts on how the relationship between the athletic and floating communities might continue to unfold.
A Skeptic’s Guide to Floating
I think it’s time we addressed the giant metaphorical elephant in the salty metaphorical room — there are lots of exaggerated and untrue claims about the benefits of floating being spread around the industry.
Some are anecdotal, some are only half true, and some are just patently false. Floating has historically had a strong oral tradition tied to it — the practice has survived through word-of-mouth, one passionate floater teaching another everything they know. The unfortunate thing about this is that the information disseminated can’t be reliably tested or shared with others on a broader scale. You can’t use “my buddy Chris” as a source for a health benefit of float tanks in a newspaper article, much less for a research paper.
Now that we’re becoming a bit more mainstream, we thought it would be nice to add some clarity to what we should and shouldn’t be telling people about these difficult-to-understand, saliferous containers.
How Many Float Tanks Should I Have?
Intro If you’ve crossed over into the sacred realm of “Yeah, I’m pretty sure I’m gonna open up a float center,” an obvious question arises — “How many tanks should I have?” Now, if you’re like me, you’re creating a 90 tank float community where everyone who buys in...